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POTS, MCAS & Hypermobility (hEDS) in Seattle

Specialized naturopathic medical care for POTS, Mast Cell Activation Syndrome (MCAS), and hypermobile Ehlers-Danlos Syndrome (hEDS) in Seattle, WA.

Many patients living with POTS, MCAS, or hypermobile Ehlers-Danlos Syndrome (hEDS) spend years searching for answers after being told their labs look “normal” despite debilitating symptoms. Our clinic provides whole-person, root-cause medical care led by licensed naturopathic doctors who understand how these interconnected conditions affect your nervous system, immune response, and daily life.

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Understanding the Trifecta: hEDS, POTS & MCAS

Postural Orthostatic Tachycardia Syndrome (POTS), Mast Cell Activation Syndrome (MCAS), and hypermobile Ehlers-Danlos Syndrome (hEDS) frequently present together in clinical practice. Connective tissue fragility in hEDS affects blood vessel elasticity, contributing to autonomic dysfunction and POTS symptoms like dizziness, rapid heart rate, orthostatic intolerance, and fatigue. At the same time, mast cells concentrated in connective tissue can become hyper-reactive, triggering widespread inflammation, food sensitivities, flushing, brain fog, and digestive distress.

Because these conditions overlap and amplify one another, treating them in isolation often leads to minimal relief. Our naturopathic doctors evaluate the whole physiological picture, calming inflammation, supporting vascular and autonomic function, and rebuilding resilience step by step.

Our Comprehensive Care Approach

At Full Circle Natural Medicine, our licensed naturopathic doctors function as primary care providers in Washington State. We combine advanced diagnostic testing with individualized treatment protocols tailored to your unique presentation:

  • Autonomic Nervous System & Volume Support: Electrolyte optimization, IV hydration protocols, compression strategies, and gentle vagal nerve regulation.
  • Mast Cell Stabilization: Natural and pharmaceutical mast cell stabilizers, targeted bioflavonoids (quercetin, luteolin), low-histamine dietary guidance, and gut mucosal healing.
  • Tissue & Structural Integrity: Specific nutrient protocols to support collagen synthesis, craniosacral therapy, and coordination with hypermobility-knowledgeable physical therapists.
  • Environmental Trigger Identification: Evaluating underlying mold/mycotoxin exposure, heavy metals, viral reactivations, and gut dysbiosis that drive persistent immune activation.

Frequently Asked Questions

Can a naturopathic doctor treat POTS and MCAS in Washington State?

Yes. Licensed naturopathic doctors (NDs) in Washington function as primary care providers. They can order diagnostic labs, issue specialist referrals, prescribe supportive medications, and utilize botanical medicine, IV hydration therapy, and dietary protocols for POTS, MCAS, and hypermobility.

What testing is used to evaluate MCAS, POTS, and hypermobility?

Evaluation includes orthostatic vitals testing (standing heart rate and blood pressure checks), serum histamine, serum tryptase, urine N-methylhistamine, prostaglandin D2, environmental mold and mycotoxin panels, Beighton score assessments for hypermobility, and comprehensive autonomic symptom scoring.

How does Full Circle Natural Medicine handle virtual vs. in-person care?

Full Circle Natural Medicine offers in-person clinic appointments in Seattle (Green Lake neighborhood) as well as telemedicine consultations for patients across Washington State and Arizona.

What is the connection between POTS, MCAS, and hypermobile Ehlers-Danlos Syndrome (hEDS)?

POTS, MCAS, and hEDS are frequently diagnosed together as a clinical triad. Lax connective tissue from hEDS causes blood pooling in lower extremities, triggering compensation from the autonomic nervous system (POTS). Meanwhile, mast cells embedded in connective tissue react to physiological stress, releasing histamine and inflammatory mediators that exacerbate dysautonomia.

Our Specialized Doctors

Care for POTS, MCAS, and hypermobility is led by providers who bring deep clinical experience in dysautonomia, environmental medicine, and complex immune conditions.